I. Responsibilities
1. Optical System Design and Simulation
Design laser excitation, fluorescence collection, and scatter light detection optical architecture for flow cytometers (including 4F imaging system, confocal optics, etc.).
Lead high numerical aperture (NA) objective lens selection, customized design, and optical performance simulation optimization (using at least one optical performance simulation software).
Model and tolerance analysis of semiconductor laser (multi-wavelength) collimation, shaping, beam combining, and focusing optical paths.
2. Optical Path Assembly and Precision Debugging
Lead opto-mechanical system assembly, 4F optical path alignment, and spatial filter implementation to ensure beam transmission precision and aberration control.
Optimize laser-sample flow-collecting objective spatial alignment to achieve micron-level focusing spot control.
Develop standardized optical path assembly procedures and fixtures to improve system consistency and maintainability.
3. Photoelectric Detection and Signal Processing
Lead selection, testing, and signal conditioning circuit design for weak light detectors such as PMT, APD, and MPPC.
Design fluorescence spectroscopy system (dichroic mirror/filter set) to optimize spectral separation efficiency and crosstalk suppression.
Develop multi-channel parallel photoelectric signal acquisition scheme to ensure high dynamic range and low distortion.
4. Noise Suppression and System Optimization
Analyze and suppress optical path noise sources (shot noise, laser intensity noise, ambient light interference, mechanical vibration coupling, etc.).
Implement opto-mechanical stability enhancement solutions (active vibration isolation, temperature control, EMI shielding, etc.).
Lead testing and iterative optimization of key indicators such as optical system sensitivity, SNR, and resolution.
5. Cross-disciplinary Collaboration and Documentation
Collaborate with electronics, software, and fluid teams for system integration and problem solving.
Write optical design reports, test specifications, BOM, and production assembly guides.
II. Requirements
1. Education
Master's degree or above in Optical Engineering, Optoelectronics, Physics, or related majors.
2. Core Experience
3+ years of precision optical system development experience; experience in flow cytometer, confocal microscope, or similar bio-optical equipment development is preferred.
Proficient in 4F imaging system principles and practices, with ability to debug complex spatial filter optical paths.
Skilled in semiconductor laser (488nm, 640nm, etc.) beam control techniques (collimation, expansion, focusing).
Experience in high NA objective lens (NA > 0.7) design/selection; deep understanding of spherical aberration and astigmatism impact on detection.
Familiar with characteristics, testing methods, and low-noise circuit design essentials of PMT/APD/MPPC detectors.
3. Tool Proficiency
Proficient in at least one optical design software.
Skilled in using optical power meters, spectrometers, oscilloscopes, vibration tables, and other test equipment.